Developing need

Developing hearts need their SPEG.

Myocardial formation is a particularly bad time to be missing building blocks and tools essential for myofibrillogenesis. Prenatal development and early postnatal development are characterized by intense cardiomyocyte formation and contractile apparatus assembly critical for normal growth and maturation. In this rapidly evolving milieu of cardiac formation, disturbances of cardiomyocyte organiz...

Do developing B cells need antigen?

Just as potentially useful T cells are positively selected by MHC-peptide complexes in the thymus, it has been proposed that self or commensal bacterial epitopes might select B cell populations with the capacity to recognize polysaccharide or protein structures on pathogens. Recent studies indicate that the repertoire of B cells entering the periphery is not shaped by specific stimuli, but that...

The Need to Customise Innovation Indicators in Developing Countries

Innovation is becoming more and more important as a driver of economic growth. In developed countries, a diverse set of innovation indicators has been developed to monitor innovation performance and the impact of innovation policies. Developing countries have been late to jump on this bandwagon and are now faced with a set of well‐established innovation indicators that might not be that well su...

Improving Cancer Care Increased Need for Radiotherapy in Developing Countries

Cancer is not a modern phenomenon – a bone tumour has been observed in a 14-year-old pharaoh who succumbed and was mummified, only to be accurately diagnosed three millennia later. Chinese and Arabic medical writings also document clinical cases so well that some can clearly be identified today as cancer from the descriptions. Cancer is a rapidly increasing problem in developing countries as st...

Rotavirus vaccine--a need of the hour in developing countries.